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Risk of bias graph (A) disease activity, (B) health-related quality of life for meta-analysis. RoB 2.0 Tool Domains: 1) Bias arising from the randomisation process; 2) Bias due to deviations from intended interventions; 3) Bias due to missing outcome data; 4) Bias in measurement of the outcome; 5) Bias in selection of the reported result; 6) Overall bias.
