Table 1. Occurrence summary of cyp51A variants by clade.
Leu98His | Gly138Cys | Pro216Leu | Gly54Glu | Gly448Ser | Met220Val | His147Tyr | |
---|---|---|---|---|---|---|---|
Clade 1 | 0 | 0 | 4 | 1 | 0 | 1 | 0 |
Clade 2 | 19 | 7 | 0 | 1 | 1 | 0 | 1 |
Clade 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Total | 19 (7.25%) | 7 (2.67%) | 4 (1.52%) | 2 (0.76%) | 1 (0.38%) | 1 (0.38%) | 1 (0.38%) |
Seven non-synonymous variants associated with antifungal drug resistance were identified in the cyp51A gene, representing 34 isolates. Percentages represent the total number of a given amino acid change across all 3 clades out of 261 isolates scanned.