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. 2022 Dec 1;11:e79543. doi: 10.7554/eLife.79543

Figure 5. Representative TEM photos of lung punches.

Panels A-C show mouse lung punches injected with gold nanoparticle labeled urine-derived exosomes from age and sex-matched control subjects (without lung disease) or U-IPFexo (panels D-H). TEM revealed exosomes in alveolar epithelial cells (AEC) type I and type II. Arrows in panels C, F, and G highlight exosomes containing nanoparticles. n=2 individual exosome preparations/group.

Figure 5.

Figure 5—figure supplement 1. Histology and trichrome staining of lung punches from C57BL6 mice.

Figure 5—figure supplement 1.

Lung punches from control lungs shown in tissue culture dish (S1A) have normal histology (S1B, Trichrome staining ×10 mag) and structure by TEM (S1C, ×500 mag). Histology of non-injected lung punch (SA1D).