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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Cell Immunol. 2022 Jun 11;378:104561. doi: 10.1016/j.cellimm.2022.104561

Fig. 3. Heatmap of female adjuvant-associated factors.

Fig. 3.

Changes in expression of adjuvant-associated factors (CFA + Ptx) in WT and each and knockout genotype with and without DRα1-MOG-35-55 treatment are shown in comparison to untreated WT mice. All groups are female mice with the severe EAE immunization regimen. Columns are sorted in descending order of adjuvant effect magnitude, representing the change in factor expression seen in CFA + Ptx adjuvant-immunized mice evaluated in a previous study [38] that exhibited cellular infiltration into the spinal cord but not demyelination or any clinical signs of EAE. An experimental effect of opposing color and equal or greater intensity would indicate reversal of the effect of adjuvant immunization on the factor.