Fig. 6. Total mean DRα1-MOG-35-55 effects on female vs. male factor expression as a fraction of total mean Vehicle-treated EAE levels.
Mean chemokine expression levels for DRα1-MOG-35-55-treated mice were summed within sex and genotype and compared to the same aggregated mean levels in the sex-and-genotype-matched Vehicle-treated (EAE) mice. The combined effects are expressed as relative changes with respect to the Vehicle-treated EAE levels, with 95% confidence intervals based on Taylor-series linearization of the variance of the ratio.