Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The pharmacophore (A) shape of 22a, and (B) the ROC of external validation showing AUC 79% (threshold 10) and 65% (threshold 100). The Enrichment Factors are 0.9 and 1.3 times greater than expected for active compounds at thresholds of 10 and 100%, respectively.
