TABLE 2.

The docking results of compounds 4 and 5 in the binding pocket of DENV2 NS2B-NS3 protease.

Ligand	ΔGbind (kcal/mol)	H-bond interacting residue	Estimated Ki (µM)
4	−9.48	ARG54, PRO132	0.11
5	−7.72	ILE36, HIS51, ARG54	2.21