Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The absorption profile evaluation results of the hits.
| Ligand | Water solubility | Caco2 permeability | Intestinal absorption (human) | Skin permeability | P-glycoprotein substrate | P-glycoprotein I inhibitor | P-glycoprotein II inhibitor |
|---|---|---|---|---|---|---|---|
| 4 | −3.417 | −0.68 | 100 | −2.735 | No | Yes | Yes |
| 5 | −3.507 | −0.257 | 100 | −2.375 | Yes | Yes | Yes |
The red colour indicates that the ligand does not meet the criteria of the corresponding parameter
