Table 4.

Summary of the prognostic significance of long non-coding RNAs in colorectal cancer.

LncRNAs	Expression	Patient No.	Univariate analysis HR (95%CI)		Multivariate analysis HR (95%CI)		Reference
			OS	PFS/DFS/RFS	OS	PFS/DFS/RFS
NEAT1_v1	Up	191	0.415(0.227–0.758)	NA	NA	NA	[165]
NEAT1_v2	Up	191	0.426(0.231–0.784)	NA	0.519 (0.280–0.965)	NA	[165]
NEAT1	Up	239	1.88(1.32–2.69)	1.93(1.38–2.71)	1.70(1.18–2.45)	1.80(1.27–2.55)	[184]
PVT-1	Up	210	2.07(1.42–3.06)	2.01(1.26–2.64)	1.76(1.16–2.37)	2.15(1.39–2.76)	[176]
HOTTIP	Down	52	NA	NA	4.949(1.685–11.984)	NA	[181]
XIST	Up	196	1.284(1.143–1.442)	1.242(1.115–1.384)	1.197(1.064–1.346)	1.165(1.044–1.300)	[173]
CCAT1	Up	135	4.06(1.47–16.8)	3.88(1.67–8.39)	5.90(2.09–24.7)	2.52(1.07–5.56)	[174]
CCAT2	Up	135	2.04(1.05–3.84)	2.55(1.19–5.31)	2.40(1.22–4.59)	2.39(1.10–5.08)	[174]
CCAT1+CCAT2	Up	135	NA	NA	8.38(2.68–37.0)	2.60(1.04–6.06)	[174]
DANCR	Up	104	2.491(1.335–7.264)	2.614(1.572–7.715)	2.131(1.157–7.058)	2.397(1.385–7.279)	[175]
SBDSP1	Up	171	2.673(1.562–5.632)	2.523(1.429–5.013)	2.137(1.238–4.672)	2.132(1.123–4.239)	[177]
BANCR	Up	106	2.74(1.52–4.96)	NA	2.24(1.22–4.16)	NA	[178]
UCA1	Up	715	2.65(1.93–3.63)	NA	2.39(1.80–3.16)	NA	[179]
AFAP1-AS1	Up	52	2.780(1.308–5.909)	2.389(1.162–4.913)	2.358(1.110–5.008)	2.120(1.032–4.353)	[182][183]
NR_029373	Down	94	NA	0.477(0.261–0.870)	NA	0.457(0.246–0.848)	[168]
NR_034119	Down	94	NA	0.561(0.316–0.996)	NA	0.517(0.277–0.964)	[168]