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. 2022 Oct 21;23(6):e89. doi: 10.4142/jvs.22124

Table 1. The distribution and the intensity of each marker at the different morphological structures.

Marker TTF-1 Napsin A SP-A CD44 CD133
Distribution of each marker
Score DS IE DS IE DS IE DS IE DS IE
Primary 2 +++ 2 +++ 1 +++ 3 +++ 2 ++
F1 1 +++ 1 +++ 1 ++ 2 ++ 1 +
F2 0 - 0 - 1 + 1 + 1 +
F2(C) 0 - 0 - 1 + 2 + 1 +
Intensity of each marker in the glandular and solid structure
Structurea G S G S G S G S G S
Primary +++ - +++ - - +++ +++ +++ +++ ++
F1 +++ - +++ - - +++ +++ ++ ++ +
F2 - - - - - + + + + +
F2(C) - - - - - + ++ ++ + +

DS (distribution of staining) was scored according to the following criteria: 0 (tumor cells were negative), 1 (5%–25% positive tumor cells), 2 (25%–60% positive tumor cells) and 3 (more than 60% positive cells); IE (intensity expression score) was based on the followings: (−) negative; (+) weak; (++) moderate; (+++) strong.

aG, glandular structure; S, solid structure.