Table 2.
Oral health parameters and dental developmental disturbances in survivors of childhood MB/CNS-PNET related to age at treatment
| Total (n = 46) | ≤ 5 years (n = 15) | > 5 years (n = 31) | p value | |
|---|---|---|---|---|
| DMFT score | ||||
| Median (IQR) | 3 (0–8) | 0 (0–4) | 4 (1–10) | 0.139 |
| Mean ± SD (min–max) | 5.2 ± 6 (0–21) | 1.7 ± 0.6 (0–6) | 6.9 ± 1.2 (0–21) | |
| Survivors with one, or more types of DDD, n (%) | 14 (30.4) | 11 | 3 | < 0.001 |
| Hypodontia | ||||
| Number of survivors, n (%) | 10 (21.7) | 7 | 3 | 0.004 |
| Number of teeth, n | 29 | 24 | 5 | |
| Microdontia | ||||
| Number of survivors, n (%) | 7 (15.2) | 6 | 1 | 0.002 |
| Number of teeth, n | 25 | 24 | 1 | |
| Enamel hypoplasia | ||||
| Number of survivors, n (%) | 4 (8.7) | 4 | No | 0.004 |
| Number of teeth, n | 10 | 10 | No | |
| Maximum mouth opening (MMO) in mm | ||||
| Median (IQR) | 40 (33.8–45) | 34 (24–37) | 42 (37–46) | 0.021 |
| Mean ± SD (min–max) | 38.5 ± 8.4 (16–55) | 33.3 ± 2.4 (16–55) | 41.1 ± 1.2 (28–51) | |
| MMO ≤ 35 mm, n (%) | 16 (35) | 10 | 6 | 0.002 |
| Mean ± SD (min–max) | 29.3 ± 5.6 (16–35) | |||
| MMO > 35 mm, n (%) | 30 (65) | 5 | 25 | |
| Mean ± SD (min–max) | 43.5 ± 4.7 (36–55) | |||
MB medulloblastoma, CNS-PNET central nervous system supratentorial primitive neuroectodermal tumor, DMFT decayed-missing-filled-teeth, IQR interquartile range, DDD dental development disturbances