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. 2022 Dec 1;12:20791. doi: 10.1038/s41598-022-19710-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Prkab1^+/− LacZ expression under Prkab1 promoter is found in multiple reproductive tissues and photoreceptor outer segments of the retina. (a) lacZ reporter shows expression in the spermatogonia layer of the testis. (b) lacZ reporter expression under the control of the Prkab1 promoter in the oviduct shows faint scattered expression. (c) lacZ reporter expression under the control of the Prkab1 promoter shows strong signal in the wavy and disorganized photoreceptor inner and outer segments. (d) Quantitative measurement of average total retina thickness, where Prkab1^+/+ n = 3698, average = 246.25 µm, SE = .148 and Prkab1^+/- n = 28, average = 241.93, SE 2.40, p-value = 0.084. No significant difference was found in total retinal thickness based on student’s two-tailed t-test. All error bars represent standard error of the mean.