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. 2022 Nov 18;13:1032070. doi: 10.3389/fendo.2022.1032070

Table 1.

Characteristics of the included studies.

No. Author Year Index PA EH Optimal cutoff value Se Sp AUC TP FP FN TN
1 Baron S 2016 ARR 107 79 45.6 pmol/mUI 1.000 0.939 NA 107 5 0 74
PAC 107 79 360 pmol/L 0.857 0.951 NA 92 4 15 75
2 Baron S 2018 PAC 82 77 308 pmol/L 0.904 0.915 0.970 74 7 8 70
ARR 82 77 64.5pmol/mU 0.873 1.000 0.988 72 0 10 77
3 Cheng Z Y 2021 ARR 57 70 6.5 pg/mL 0.942 0.78 0.902 54 15 3 55
PAC 57 70 24 pg/mL 0.872 0.788 0.876 50 15 7 55
4 Fan Jing 2020 UAC 55 78 11.6 μg/24h 0.509 0.808 0.659 28 15 27 63
UARR 55 78 4.63(μg/24h)/(μg/L/h) 0.855 0.821 0.906 47 14 8 64
5 Fries C M 2020 PAC 32 67 83 pmol/L 0.969 0.925 NA 31 5 1 62
ARR 32 67 53 pmol/mU 0.969 0.597 NA 31 27 1 40
6 Fuss C T 2021 PAC 103 84 68ng/L 0.796 0.893 0.908 82 9 21 75
7 Guo Z 2018 ARR 29 8 55 pmol/mU 0.931 0.875 NA 27 1 2 7
8 Juutilainen Auni 2014 ARR 8 31 44 pmol/ng 1.000 0.84 0.970 8 5 0 26
9 Ma W 2019 UARR 60 353 1.11(μg/24h)/(μIU/ml) 0.917 0.890 0.947 55 39 5 314
ARR 60 353 2.60(ng/dl)/(μIU/ml) 0.933 0.901 0.958 56 35 4 318
UAC 60 353 7.13 μg/24 h 0.783 0.567 0.725 47 153 13 200
10 Travers S 2019 UAC 64 107 65 nmol/24 h 0.766 0.785 0.864 49 23 15 84
11 Xu Wen 2019 ARR 27 333 NA 0.910 0.963 NA 25 12 2 321
12 Zhao Lin 2019 ARR 143 232 13.84 (ng/dl)/(ng/ml·h) 0.790 0.783 0.837 113 50 30 182
PAC 143 232 4.29 ng/dl 0.696 0.906 0.807 100 22 43 210

PA, Primary aldosteronism; EH, essential hypertension; Se, sensitivity; Sp, specificity; AUC, area under the receiver operating characteristic curve; TP, true positive; FP, false positive; TN, true negative; FN, false negative.