Table 5.
Relative abundance of the functional microbiome predicted by KEGG second-level pathways between chicks from the control and FMT groups estimated using the statistical analysis of metagenomic profiles.
| Categories of KEGG second-level pathways 1 | Control | FMT | SEM | P-Value |
|---|---|---|---|---|
| Cellular Processes | ||||
| Cell growth and death | 0.0060 | 0.0080 | 0.0000 | 0.0001** |
| Cell motility | 0.0120 | 0.0180 | 0.0020 | 0.0720 |
| Transport and catabolism | 0.0010 | 0.0020 | 0.0000 | 0.0001** |
| Unclassified; Cellular Processes and | 0.0340 | 0.0570 | 0.0040 | 0.0590* |
| Environmental Information Processing | ||||
| Membrane transport | 0.1280 | 0.1370 | 0.0030 | 0.004** |
| Signaling molecules and interaction | 0.0020 | 0.0010 | 0.0001 | 0.006** |
| Signal transduction | 0.0130 | 0.0150 | 0.0000 | 0.008** |
| Genetic Information Processing | ||||
| Folding, sorting and degradation | 0.0230 | 0.0230 | 0.0002 | 0.935 |
| DNA replication and repair | 0.0890 | 0.1000 | 0.0020 | 0.003** |
| Transcription | 0.0090 | 0.0270 | 0.0005 | 0.007** |
| Translation | 0.0570 | 0.0670 | 0.0010 | 0.002** |
| Unclassified; Genetic Information | 0.0260 | 0.0250 | 0.0003 | 0.035* |
| Immune Information Processing | ||||
| Immune system diseases | 0.0010 | 0.0010 | 0.0000 | 0.616 |
| Infectious diseases | 0.0040 | 0.0030 | 0.0000 | 0.041* |
| Metabolic diseases | 0.0010 | 0.0010 | 0.0000 | 0.205 |
| Neurodegenerative diseases | 0.0010 | 0.0010 | 0.0000 | 0.884 |
| Metabolism Processing | ||||
| Amino acid metabolism | 0.0770 | 0.0930 | 0.0030 | 0.001** |
| Biosynthesis secondary metabolites | 0.0020 | 0.0080 | 0.0002 | 0.001** |
| Carbohydrate metabolism | 0.1110 | 0.4510 | 0.0010 | 0.004** |
| Energy metabolism | 0.0530 | 0.0910 | 0.0072 | 0.032* |
| Enzyme families | 0.0170 | 0.0420 | 0.0006 | 0.025* |
| Glycan biosynthesis and metabolism | 0.0220 | 0.0860 | 0.0003 | 0.090 |
| Lipid metabolism | 0.0290 | 0.0310 | 0.0008 | 0.099 |
| Cofactors and vitamins | 0.0340 | 0.0570 | 0.0010 | 0.003** |
| Other amino acids | 0.0150 | 0.0210 | 0.0003 | 0.074 |
| Terpenoids and polyketides | 0.0080 | 0.0070 | 0.0004 | 0.286 |
| Nucleotide metabolism | 0.0470 | 0.0420 | 0.0010 | 0.046* |
| Xenobiotics biodegradation | 0.0230 | 0.0240 | 0.0010 | 0.648 |
| Unclassified; Metabolism Processing | 0.0230 | 0.0870 | 0.0080 | 0.009* |
| Organismal Systems | ||||
| Circulatory system | 0.0000 | 0.0000 | 0.0000 | 0.717 |
| Digestive system | 0.0010 | 0.0050 | 0.0000 | 0.025 |
| Endocrine system | 0.0010 | 0.0060 | 0.0000 | 0.001 |
| Excretory system | 0.0003 | 0.0002 | 0.0000 | 0.079 |
| Immune system | 0.0005 | 0.0002 | 0.0000 | 0.048 |
| Nervous system | 0.0010 | 0.0010 | 0.0000 | 0.968 |
| Unclassified; Poorly Characterized | 0.0500 | 0.0480 | 0.0020 | 0.003 |
1 All data are expressed as the mean ± SEM of the relative abundance for predicting of functional microbiome; Values between groups are significantly different (*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001). (n=11/group).