Table 2.
Results of a multiple linear regression analysis with mean deviation of automated static perimetry* in the worse eye as a dependent variable in patients with primary open-angle glaucoma.
Independent variables | Beta† (95% CI) | SE | P value |
---|---|---|---|
Age, years | − 0.17 to − 0.16 (− 0.22 to − 0.11) | 0.027–0.028 | < 0.001 |
Male sex | − 2.07 to − 1.93 (− 3.55 to − 0.47) | 0.74–0.75 | 0.0059–0.0095 |
GRS of 5 optic nerve-related genetic variants | 0.047 (− 0.60 to 0.69) | 0.33 | 0.89 |
GRS of 17 IOP-related genetic variants | − 0.51 (− 0.81 to − 0.20) | 0.15 | 0.0012 |
CI confidence interval, SE standard error, GRS genetic risk score, IOP intraocular pressure.
*Humphrey field analyzer 30–2 (HFA30-2), †Regression coefficient.
F change = 13.1–17.0, P < 0.001.