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. 2022 Dec 1;12:20744. doi: 10.1038/s41598-022-24915-x

Table 2.

Results of a multiple linear regression analysis with mean deviation of automated static perimetry* in the worse eye as a dependent variable in patients with primary open-angle glaucoma.

Independent variables Beta (95% CI) SE P value
Age, years − 0.17 to − 0.16 (− 0.22 to − 0.11) 0.027–0.028  < 0.001
Male sex − 2.07 to − 1.93 (− 3.55 to − 0.47) 0.74–0.75 0.0059–0.0095
GRS of 5 optic nerve-related genetic variants 0.047 (− 0.60 to 0.69) 0.33 0.89
GRS of 17 IOP-related genetic variants − 0.51 (− 0.81 to − 0.20) 0.15 0.0012

CI confidence interval, SE standard error, GRS genetic risk score, IOP intraocular pressure.

*Humphrey field analyzer 30–2 (HFA30-2), Regression coefficient.

F change = 13.1–17.0, P < 0.001.