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. 2022 Dec 1;13:7419. doi: 10.1038/s41467-022-35094-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a UMAP visualization of PBMC data before integration colored by omics and cell annotations. b UMAP visualization of PBMC data after uniPort integration. c Comparison of total scores of ARI, NMI and F1 of different methods. d Comparison of Batch Entropy scores and Silhouette coefficients of different methods. e Comparison of average FOSCTTM of different methods.