Table 5.

Multivariable predictive model of reaching maximum recommended dose of Sac/Val

Variables	Odds ratio	95% confidence interval	p
Age ≥60 years	0.202	0.06–0.675	0.009
SBP ≥ 125 mmHg	2.942	1.021–8.480	0.046
Baseline TAPSE ≥16 mm	3.744	1.054–13.3	0.041
ACE/ARBs maximum dose at baseline	3.496	1.289–9.481	0.014

SBP, systolic blood pressure; TAPSE, tricuspid annular plane systolic excursion; ACEi/ARBs, angiotensin converting enzyme inhibitors/angiotensin receptor blockers. We have reported in bold the statistically significant P‐value.