Table 2.
Baseline clinical characteristics of included patients
| Study | Age (years) | Male (%) | Diabetes (%) | Atrial fibrillation (%) | NYHA ≥III (%) | LVEF (%) | Left ventricular end‐diastolic volume (mL) | MR grade ≥3 (%) | N of clips implanted per patient |
|---|---|---|---|---|---|---|---|---|---|
| MITRA‐FR 23 | 70.1 | 78.9 | 32.9 | 34.5 | 63.1 | 33.3 | 136.2 ± 37.4 † | 48 | 1.2 |
| COAPT 15 | 71.7 | 66.6 | 35.1 | 57.3 | 57 | 31.3 | 194.4 ± 69.2 | 100 | 1.7 |
| Godino et al. 20 | 69 | 77 | 33 | 47 | 78 | 30.8 | 217.1 ± 77.1 | 94.8 | 1.7 |
| Kitamura et al. 24 | 73.6 | 68.9 | 47.9 | 64.5 | 85.3 | 32.1 | — | — | — |
| TRAMI 25 | 74.5 | 70.7 | — | — | 91.3 | — | — | 100 | 1.4 |
| Pilot European Sentinel 21 | 72.8 | 68 | 33 | 27 | 88 | 37.1 | 171.1 ± 90.2 | 40.8 | 1.4 |
| GRASP‐IT 17 | 71.1 | 68.3 | 37.9 | 41.6 | 18 | 32.5 | 174 ± 83 | 67.9* | 1.3 |
| Overall | 71.8 | 71.2 | 36.6 | 45.3 | 68.7 | 32.8 | — | 75.2 | 1.4 |
LVEF, left ventricular ejection fraction; MR, mitral regurgitation; NYHA, New York Heart Association.
*
Including only MR Grade 4.
†
mL/m2.