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. 2022 Jul 15;9(5):3393–3406. doi: 10.1002/ehf2.14070

Table 3.

Results of the predictor analyses for the inter‐individual response variability in peak V̇O2 for the main and per protocol analysis

Mean change in relative peak V̇O2 [β‐coefficient (95% CI), P‐value] Interaction P for exercise training vs. guideline control
Exercise training Guideline control [N = 52]* Main analysis Per protocol analysis
Complete set [N = 106]* Per protocol set [N = 87]*
Peak O2‐pulse (per 1 mL/beat) −1.45% (−2.30 to −0.60), P = 0.001 −1.88% (−2.79 to −0.97), P < 0.001 −0.08% (−1.11 to 0.96), P = 0.88 0.04 0.01
Peak V̇O2 (per 1 mL/kg/min) −0.38% (−0.99 to 0.22), P = 0.17 −0.26% (−0.98 to 0.45), P = 0.47 −0.39% (−1.10 to 0.32), P = 0.28 0.97 0.78
Peak V̇O2 (per 100 mL/min) −0.76% (−1.45 to 0.07), P = 0.03 −0.74% (−1.51 to 0.02), P = 0.06 −0.17% (−1.03 to 0.69), P = 0.70 0.31 0.34
Peak heart rate (per 10 b.p.m.) 0.42% (−0.79 to 1.63), P = 0.50 0.74% (−0.57 to 2.06), P = 0.27 −0.48% (−1.96 to 0.99), P = 0.52 0.35 0.22
Weight (per 10 kg) −1.11% (−2.84 to 0.63), P = 0.21 −2.04% (−4.15 to 0.08), P = 0.06 1.35% (−1.35 to 4.05), P = 0.32 0.14 0.054
Haemoglobin (per 1 mg/dL)* 0.10% (−1.81 to 2.00), P = 0.92 0.21% (−1.91 to 2.33), P = 0.85 1.60% (−1.46 to 4.65), P = 0.30 0.44 0.49
*

Different N for the analyses including haemoglobin (exercise training complete set: 103; exercise training per‐protocol set: 84; guideline control: 52). V̇O2, oxygen consumption.