Table 2.
Percentage of gated cells in G0/G1, S, and G2/M phases. Asterisk (*) represents a significant difference compared to ctrl1 (p < 0.05). Dagger (†) represents a significant difference compared to ctrl2 (p < 0.05). Each test was conducted in triplicate (n = 3)
| Leptin + AP (Methanol) | ||||||
|---|---|---|---|---|---|---|
| Leptin | AP | Cis | G0/G1 (%) | S (%) | G2/M (%) | |
| ctrl1 | ✗ | ✗ | ✗ | 76.23 ± 0.47 | 7.83 ± 0.42 | 14.30 ± 0.26 |
| ctrl2 | ✔ | ✗ | ✗ | 72.70 ± 0.61* | 10.67 ± 0.21* | 14.87 ± 0.45 |
| ic10 | ✔ | IC10 | ✗ | 62.77 ± 0.67† | 15.53 ± 0.78† | 19.77 ± 0.06† |
| ic25 | ✔ | IC25 | ✗ | 61.63 ± 1.64† | 21.13 ± 0.55† | 15.50 ± 0.95 |
| cisplatin | ✔ | ✗ | IC10 | 20.30 ± 0.35† | 44.37 ± 0.32† | 31.83 ± 0.49† |
| Adipocyte CM + AP (Methanol) | ||||||
| CM | AP | Cis | G0/G1 (%) | S (%) | G2/M (%) | |
| ctrl1 | ✗ | ✗ | ✗ | 79.40 ± 0.69 | 4.17 ± 0.45 | 15.13 ± 0.32 |
| ctrl2 | ✔ | ✗ | ✗ | 72.93 ± 2.27 | 7.43 ± 0.42* | 17.97 ± 1.80 |
| ic10 | ✔ | IC10 | ✗ | 62.47 ± 6.92 | 18.83 ± 6.82 | 17.03 ± 0.51 |
| ic25 | ✔ | IC25 | ✗ | 37.10 ± 5.94† | 44.07 ± 5.95† | 17.00 ± 0.78 |
| cisplatin | ✔ | ✗ | IC10 | 31.40 ± 3.92† | 22.07 ± 1.12† | 43.57 ± 3.53† |
| Leptin = 100 ng/mL; CM = 10%; APE2 IC10 = 24.11 µg/mL, IC25 = 42.11 µg/mL; Cisplatin IC10 = 4.11 µg/mL | ||||||