Table 2.

Stroke patients with NIHSS score severity and RGMA levels.

Characteristic or investigation	Total (n = 90)	Admission NIHSS ˂ 8 (n = 60, 66.7%)	Admission NIHSS ≥ 8 (n = 30, 33.3%)	p Value
Age, Mean, years	47.3 ± 9.8	48.4 ± 9.6	45.0 ± 9.8	0.12
Sex (Male)	81 (90)	55 (91.7)	26 (86.7)	0.46
(Female)	9 (10)	5 (8.3)	4 (13.3)
Hypertension	65 (72.2)	45 (75)	20 (66.7)	0.40
Diabetes	40 (44.4)	31 (51.7)	9 (30.0)	0.05
Dyslipidemia	88 (97.8)	58 (96.7)	30 (100.0)	0.31
Coronary artery disease	6 (6.7)	4 (6.7)	2 (6.7)	1.00
Atrial fibrillation on admission	3 (3.3)	1 (1.7)	2 (6.7)	0.21
Active smoking	46 (51.1)	33 (55)	13 (43.3)	0.29
History of stroke	7 (7.8)	6 (10)	1 (3.3)	0.27
Obesity (BMI ≥ 30 kg/m2)	17 (18.9)	12 (20)	5 (16.7)	0.70
Modified Rankin Score—at discharge
0	21 (23.3)	12 (20.0)	9 (30.0)	0.01
1	13 (14.4)	7 (11.7)	6 (20.0)
2	16 (17.8)	15 (25.0)	1 (3.3)
3	8 (8.9)	8 (13.3)	0
4	32 (35.6)	18 (30.0)	14 (46.7)
5	–	–	–
6	–	–	–
Modified Rankin Score—at 90 days
0	52 (57.8)	33 (55.0)	19 (63.3)	0.26
1	14 (15.6)	11 (18.3)	3(10.0)
2	11 (12.2)	8 (13.3)	3(10.0)
3	9 (10.0)	4 (6.7)	5 (16.7)
4	4 (4.4)	4 (6.7)	0
5	–	–	–
6	–	–	–
RGMA mRNA level day 1, fold (mean ± SEM)	2.1519 ± 1.8259	1.8367 ± 1.6029	2.7519 ± 2.0872	0.02
RGMA mRNA level day 5, fold (mean ± SEM) (n = 82)	3.9391 ± 3.2382	3.2864 ± 3.0322	5.1319 ± 3.3134	0.01
RGMA mRNA level day 1 severity
Mild	19 (21.1)	16 (27.1)	3 (19.7)	0.068
Moderate	37 (41.1)	25 (42.4)	12 (38.7)
Severe	34 (37.8)	18 (30.5)	16 (51.6)
RGMA mRNA level day 5 severity (n = 82)
Mild	10 (12.2)	9 (17.0)	1 (3.4)	0.02
Moderate	29 (35.4)	22 (41.5)	7 (24.1)
Severe	43 (52.4)	22 (41.5)	21 (72.4)