Table 1.

Univariate and multivariate Logistics regression for pulmonary metastasis of osteosarcoma.

Characteristics	Univariate logistics regression			Multivariable logistics regression
	OR	CI	P	OR	CI	P
Age	1	1-1.01	0.637	NA	NA	NA
Bone metastases
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	8.58	4.92-14.96	<0.001	5.29	2.88-9.73	<0.001
Chemotherapy
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	1.48	0.99-2.22	0.058	NA	NA	NA
Grade
Well differentiated	Ref	Ref	Ref	Ref	Ref	Ref
Moderately differentiated	3.61	0.4-32.75	0.254	NA	NA	NA
Poorly differentiated	6.39	0.85-48.03	0.072	NA	NA	NA
Undifferentiated; anaplastic	5.95	0.8-44.32	0.082	NA	NA	NA
unknown	5.11	0.68-38.58	0.113	NA	NA	NA
Laterality
Left	Ref	Ref	Ref	Ref	Ref	Ref
Right	1.13	0.83-1.56	0.431	NA	NA	NA
Other	0.84	0.51-1.37	0.475	NA	NA	NA
Lymph node Sur
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	0.56	0.33-0.95	0.031	0.83	0.47-1.45	0.512
N
N0	Ref	Ref	Ref	Ref	Ref	Ref
N1	2.61	1.28-5.31	0.008	1.54	0.67-3.57	0.31
NX	2.82	1.72-4.62	<0.001	2.06	1.17-3.62	0.012
Primary Site
	Ref	Ref	Ref	Ref	Ref	Ref
Primary Site1	0.82	0.58-1.17	0.271	NA	NA	NA
Primary Site2	0.81	0.46-1.43	0.471	NA	NA	NA
Race
White	Ref	Ref	Ref	Ref	Ref	Ref
Black	1.12	0.72-1.72	0.62	NA	NA	NA
Other	1.08	0.73-1.59	0.7	NA	NA	NA
Radiation
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	1.74	1.16-2.6	0.007	1.38	0.87-2.19	0.174
Sex
Male	Ref	Ref	Ref	Ref	Ref	Ref
Female	0.63	0.46-0.85	0.003	0.57	0.41-0.79	0.001
Surgery
No	Ref	Ref	Ref	Ref	Ref	Ref
Yes	0.27	0.2-0.38	<0.001	0.39	0.27-0.58	<0.001
T
T1	Ref	Ref	Ref	Ref	Ref	Ref
T2	2.56	1.73-3.78	<0.001	2.46	1.63-3.71	<0.001
T3	6.03	2.93-12.41	<0.001	4.29	1.94-9.52	<0.001
TX	3.58	2.23-5.73	<0.001	2.23	1.31-3.77	0.003

OR, odds ratio; CI, confidence interval; Ref, reference; NA, not available.