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. 2022 Nov 18;13:1061431. doi: 10.3389/fneur.2022.1061431

Table 5.

Results of GRADE assessment.

Author(s), year Outcomes Studies (participants) Limitations Inconsistency Indirectness Imprecision Publication bias Quality
Gong et al. (16) Response
AT vs. MT 1(60) −1 −1 0 0 −1 VL
AT vs. WAT 1(62) −1 −1 0 0 −1 VL
AT vs. EAT 1(128) −1 −1 0 0 0 L
BAT vs. AAT 1(147) −1 −1 0 −1 0 VL
AT+MT vs. MT 2(140) −1 −1 0 −1 0 VL
AT vs. EAT+MT 1(68) −1 −1 0 0 −1 VL
Zhang et al. (17) Response
AT vs. MT 10(633) −1 0 0 −1 0 L
THI
AT vs. MT 3(173) −1 0 0 −1 0 L
AT vs. SAT 2(90) −1 −1 0 −1 0 VL
Song et al. (18) Response
AT vs. MT 9(1174) −1 0 0 0 0 M
Ji et al. (19) Response
AT vs. MT 7(678) −1 0 0 0 −1 L
AT+MT vs. MT 4(511) −1 0 0 0 −1 L
EAT+AI vs. MT 2(132) −1 0 0 0 −1 L
MT+AP vs. MT 2(196) −1 0 0 0 −1 L
Meng et al. (20) Response
AT vs. MT 8(851) −1 0 0 0 0 M
OAT vs. CAT 10(774) −1 0 0 0 0 M
AT+MT vs. MT 4(324) −1 0 0 0 0 M
AT+MT vs. AT 4(184) −1 0 0 0 0 M
Nie et al. (21) Response
AT vs. MT 3(250) −1 0 0 −1 −1 VL
AT+MT vs. MT 2(200) −1 0 0 −1 −1 VL
AT+CPM vs. MT 1(73) −1 0 0 −1 −1 VL
Ma et al. (22) Response
AT vs. MT 7(496) −1 0 0 0 −1 L
AT+CPM vs. MT 4(324) −1 0 0 0 −1 L
AT vs. SAT 4(244) 0 0 0 0 −1 M
Fang et al. (23) Response
EAT vs. AT 6(443) −1 0 0 0 −1 L
EAT+CPM vs. MT 8(759) −1 0 0 0 −1 L
EAT vs. CT 14(1202) −1 0 0 0 −1 L
Xie et al. (24) Response
AT vs. MT 5(358) −1 0 0 0 0 M
AT vs. CM 2(122) −1 0 0 0 0 M
AT+MT vs. MT 2(155) −1 0 0 0 0 M
AT+CM vs. CM 3(334) −1 0 0 0 0 M
Liu et al. (25) Response
AT vs. SAT 2(66) 0 0 0 0 −1 M
AT vs. MT 3(190) 0 0 0 −1 −1 L
AT+CT vs. CT 1(64) 0 0 0 −1 −1 L
EAT vs. MT 3(240) 0 0 0 −1 −1 L
AT+MT vs. AT 1(54) 0 0 0 −1 −1 L
AT+MT vs. MT 1(100) 0 0 0 0 −1 M
He et al. (26) Response
EAT vs. AT 1(128) −1 0 0 0 −1 L
EAT vs. PAT 2(64) 0 0 0 0 −1 M
EAT+CPM+PT vs. CPM+PT 1(60) −1 0 0 0 −1 L
EAT+CPM vs. MT 1(60) −1 0 0 0 −1 M
Huang et al. (27) VAS
AT vs. SAT 4(263) 0 0 0 −1 0 M
AT vs. MT 1(64) −1 0 0 −1 0 L
WAT vs. MT 2(117) −1 0 0 −1 0 L
THI
AT vs. SAT 1(57) 0 0 0 −1 0 M
WAT vs. MT 2(117) −1 0 0 −1 0 L
AT vs. MT 1(64) −1 0 0 −1 0 L
AT vs. CT 1(70) −1 0 0 −1 0 L
TSI
AT vs. SAT 2(142) −1 0 0 −1 0 L
Kim et al. (28) Response
AT vs. SAT 7(293) 0 0 0 −1 0 M
AT vs. MT 2(150) −1 0 0 −1 0 L
Park et al. (29) Response
AT vs. SAT 2(75) −1 −1 0 0 −1 VL
VAS
AT vs. SAT 3(88) −1 −1 0 0 −1 VL
TA vs. CT 1(22) −1 −1 0 0 −1 VL

VS, versus; AT, acupuncture; MT, medication therapy; WAT, warm acupuncture; EAT, electroacupuncture; BAT, body acupuncture; AAT, abdominal acupuncture; AI, acupoint injection; AP, acupoint application; CPM, Chinese patent medicine; SAT, sham acupuncture; OAT, other acupuncture; CAT, conventional acupuncture; CT, conventional therapy; PAT, placebo acupuncture; PT, Psychotherapy; VAS, visual analog scale; THI, tinnitus handicap inventory; TIS, tinnitus severity index; VL, very low; L, low; M, moderate.