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. 2022 Oct 31;24(6):737. doi: 10.3892/etm.2022.11673

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Copyright: © Tan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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KLF2 overexpression increases viability of ox-LDL-induced HUVECs. The (A) protein and (B) mRNA expressions of KLF2 in ox-LDL-induced HUVECs were determined by western blotting and RT-qPCR analysis. The (C) protein and (D) mRNA expressions of KLF2 in HUVECs transfected with pcDNA3.1-KLF2 were determined by western blotting and RT-qPCR analysis. The (E) protein and (F) mRNA expressions of KLF2 in ox-LDL-induced HUVECs transfected with pcDNA3.1-KLF2 were determined by western blotting and RT-qPCR analysis. (G) The viability of ox-LDL-induced HUVECs transfected with pcDNA3.1-KLF2 was detected by CCK-8 assay. ^**P<0.01 and ^***P<0.001. KLF2, Krüppel like transcription factor 2; ox-LDL, oxidized low-density lipoprotein; HUVECs, human umbilical vein endothelial cells; RT-qPCR, reverse transcription-quantitative PCR; NC, negative control.