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. 2022 Nov 29;63(12):30. doi: 10.1167/iovs.63.12.30

Table 2.

Summary of Functional Assays Conducted During This Study and the Molecular Interactions of FH Assessed in Each Assay

Assays Binding to C3b Competition With FB Binding and/or Displacement of Bb Recruitment of FI to C3bBb Recognition of Host Surface
C3b binding +
DAA + +
Cofactor + +
AP immunoassay + + +
Hemolysis + + + +