TABLE 1.
CFU present in brains of mice on days 1, 3, 7, and 14 after i.v. infection with C. neoformans
Day after infection | Mean ± SEM CFU/brain in mice treated witha:
|
P | |
---|---|---|---|
Saline-IFA | CneF-IFA | ||
1 | 1,004 ± 23 | 692 ± 46 | <0.006 |
3 | 7.4 × 104 ± 3.6 × 103 | 2.0 × 104 ± 2.2 × 103 | <0.001 |
7 | 22.4 × 106 ± 1.4 × 106 | 2.6 × 106 ± 0.95 × 106 | <0.002 |
14 | 48.5 × 106 ± 12.0 × 106 | 1.1 × 106 ± 0.51 × 106 | <0.007 |
Three mice from each group were analyzed for brain CFU at each time. The data are representative of one experiment that was performed twice, with similar results.