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. 2022 Dec 1;5(12):e2244514. doi: 10.1001/jamanetworkopen.2022.44514

Table 2. Sleep Quality, Anxiety, and Depression Scores on Postoperative Days (PODs) 1 and 3a.

Median (IQR) P value
Control group (n = 91) Esketamine group (n = 92)
POD 1
Sleep quality
AIS score 3 (2-6) 2 (2-3) .01
NRS score 5 (5-6) 5 (4-5) <.001
PSD, No. (%) 40 (44.0) 21 (22.8) .002
HADS-A score 5 (4-6) 5 (4-6) .71
HADS-D score 2 (2-3) 2 (2-3) .43
POD 3
Sleep quality
AIS score 3 (2-3) 2 (2-3) .06
NRS score 4 (4-5) 4 (4-5) .05
PSD, No. (%) 18 (19.8) 7 (7.6) .02
HADS-A score 4 (4-5) 4 (3-5) .68
HADS-D score 2 (2-2) 2 (2-3) .75

Abbreviations: AIS, Athens Insomnia Scale; HADS-A, Hospital Anxiety and Depression Scale-Anxiety; HADS-D, Hospital Anxiety and Depression Scale-Depression; NRS, numeric rating scale; PSD, postoperative sleep disturbance.

a

Data presented as median (IQR) were compared using the Mann-Whitney test. Data reported as the number of patients (%) were compared using the Pearson χ2 test or Fisher exact test.