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Table 4.

High- and low-risk histological subtypes of DTC and high-risk pathologic characteristics for extent of disease

High risk Low risk
A. Histological subtypes
Tall cell variant of PTC Follicular variant of PTC
Diffuse sclerosing variant of PTC Classic variant of PTC
Solid/trabecular variant of PTC Encapsulated PTC
Poorly differentiated carcinoma
B. High-risk characteristics found at pathological examination
Multifocal disease
Bilateral disease
Extracapsular invasion
Extra thyroidal extension

Table based on Balachander et al. (45), Baumgarten et al. (52), Jain et al. (51).