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. 2022 Dec 2;22:1250. doi: 10.1186/s12885-022-10315-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — MR images of a 65-year-old woman with invasive ductal carcinoma of the left breast before NAC. A TWIST-DCE image. B–H Pseudocolor images for determining K^trans (B), K_ep (C), IAUC (D), W-in (E), W-out (F), TTP (G), and ADC (H). Red represents high values, yellow intermediate values, and blue low values. The values for K^trans, K_ep, IAUC, W-in, W-out, and TTP were 0.309 min^-1, 1.136 min^-1, 0.336, 0.499 min^-1, 0.013 min^-1, 0.582 minutes and 0.849×10^-3 mm²/s, respectively