Table 5.

Diagnostic performance of all parameters in predicting pCR after NAC

Parameters	AUC	Cutoff	Sensitivity	Specificity	PPV	NPV	P value
Ktrans (min-1)	0.825	≤0.073	83.33	75.79	0.433	0.998	<0.001*
Kep (min-1)	0.805	≤0.169	62.50	92.63	0.257	0.965	<0.001*
Ve(%)	0.542	≤0.204	45.83	71.58	1.064	0.919	0.572
IAUC	0.824	≤0.083	83.33	78.95	0.388	0.998	<0.001*
ADC	0.721	>0.981	87.50	56.84	0.312	0.998	<0.001*
W-in	0.866	≤0.092	83.33	84.21	1.095	0.397	<0.001*
W-out	0.572	>0.009	62.50	58.95	0.623	0.405	0.238
TTP	0.725	>0.582	100.00	42.11	0.304	0.457	<0.001*
Ktrans + Kep +IAUC	0.836	>-0.721	70.83	85.26	0.642	0.724	<0.001*
Ktrans+Kep+IAUC+ADC	0.845	>-0.223	62.50	95.79	0.657	0.973	<0.001*
W-in+TTP	0.865	>-0.684	83.33	84.21	0.486	0.735	<0.001*
W-in+TTP+ADC	0.886	>-0.811	87.50	82.11	0.441	0.711	<0.001*

*P value <0.05, indicating that the differences were considered statistically significant. Abbreviations: PPV Positive predictive value, NPV Negative predictive value