Fig. 7.

Analysis of overlapping datasets regulated by METTL4/6mA, lncRNA RP11-390F4.3, and HIF-1α, and a summary model. a Venn diagram shows the number of genes that was co-regulated by METTL4/6mA, lncRNA RP11-390F4.3, and HIF-1α. b KEGG analysis of the 92 co-regulated genes, in which glycolysis and HIF-1 signaling pathways are on the top of the list. c Categorization of the 92 genes shows that they mainly belonged to the main hypoxia-induced phenotypes (angiogenesis, stemness, cancer metabolism). d A model to summarize the results and the mechanisms from this report