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. 2022 Dec 1;12(12):e063023. doi: 10.1136/bmjopen-2022-063023

Table 1.

Study characteristics.

Characteristics (41 studies, 1918 patients)
Range of publication year 1989–2021
Median (IQR) no of patients 11 (5–29)
Geographical region
 North America 19 (46)
 Europe 14 (34)
 Central/South America 0 (0)
 Asia 4 (10)
 Other 4 (10)
Study design
 Randomised trial 1 (2)
 Cohort 19 (46)
 Case-control 2 (5)
 Case-series 19 (46)
Case definition
 Probable STSS patients 115 (6)
 Confirmed STSS patients 227 (12)
Prognostic factor type
 Demographic 29 (71)
 Medical history 5 (12)
 Early disease 11 (27)
 Treatment 16 (39)

Values are numbers (percentages) of studies unless stated otherwise. Medical history included prognostic variable: immunocompromised. Early disease included prognostic variables: necrotising fasciitis, acute renal failure.

STSS, streptococcal toxic shock syndrome.