Table 2.
Management of Hospitalized Patients
| Hospitalized Patients with PH (n = 126) | Patients with PH Discharged Alive (n = 74) | Deceased Patients with PH (n = 52) | P Value | |
|---|---|---|---|---|
| PH network | 68 (54.0%) | 42 (56.8%) | 26 (50.0%) | 0.45 |
| Outside PH network | 58 (46.0%) | 32 (43.2%) | 26 (50.0%) | |
| PCR positive | 119 (94.4%) | 70 (94.6%) | 49 (94.2%) | 0.76 |
| Nosocomial COVID-19 | 24 (19.0%) | 13 (17.6%) | 11 (21.2%) | 0.61 |
| Extent of CT opacities (n = 89) | 0.06 | |||
| <25% | 35 (39.3%) | 25 (45.5%) | 10 (29.4%) | |
| 25–50% | 34 (38.2%) | 22 (40%) | 12 (35.3%) | |
| >50% | 20 (22.5%) | 8 (14.5%) | 12 (35.3%) | |
| Acute pulmonary embolism | 5 (4.0%) | 4 (5.4%) | 1 (1.9%) | 0.32 |
| Right heart failure | 38 (30.2%) | 15 (20.3%) | 23 (44.2%) | <0.01 |
| Acute renal failure | 25 (19.8%) | 8 (10.8%) | 17 (32.7%) | <0.01 |
| C-reactive protein, mg/l (n = 98) | 59 [31-95] | 52 (30–94) | 63 [34–117] | 0.32 |
| Lymphocytes (n = 76) | 690 [480–1,240] | 715 [500–1,255] | 585 [420–1,218] | 0.27 |
| D-dimer (n = 53) | 698 [324–1,692] | 630 [305–1,678] | 780 [430–2,045] | 0.73 |
| BNP > 300 or NT-proBNP > 1,400 ng/L (n = 77) | 42 (54.5%) | 20 (47.6%) | 22 (62.9%) | 0.18 |
| In-hospital management | ||||
| Critical care | 58 (46.0%) | 32 (43.2%) | 26 (50.0%) | 0.45 |
| Limitation of care | 31 (24.2%) | 6 (8.0%) | 25 (47.2%) | <0.001 |
| Length of stay, d | 9 (5–15) | 11 (7–18) | 5 (2–14) | <0.001 |
| Corticosteroids | 68 (54.0%) | 40 (53.3%) | 28 (52.8%) | 0.98 |
| High-flow oxygen | 47 (37.3%) | 24 (32.4%) | 23 (44.2%) | 0.18 |
| Invasive mechanical ventilation | 14 (11.1%) | 5 (6.8%) | 9 (17.3%) | 0.12 |
| ECMO | 2 (1.6%) | 1 (1.3%) | 1 (1.9%) | — |
Definition of abbreviations: BNP = brain natriuretic peptide; COVID-19 = coronavirus disease; CT = computed tomography; ECMO = extracorporeal membrane oxygenation; NT-proBNP = N-terminal pro–brain natriuretic peptide; PH = pulmonary hypertension.