Table 3.
Variables | n | Univariable |
Multivariable Model A |
Multivariable Model B |
||||||
---|---|---|---|---|---|---|---|---|---|---|
Odds Ratio | 95% CI | P Value | Odds Ratio | 95% CI | P Value | Odds Ratio | 95% CI | P Value | ||
Age (per year) | 126 | 1.04 | 1.01–1.07 | 0.012 | 1.04 | 1.00–1.07 | 0.044 | — | — | — |
Male sex | — | 2.42 | 1.16–5.07 | 0.019 | 2.46 | 1.12–5.40 | 0.025 | — | — | — |
PH diagnosis | 126 | — | — | — | — | — | — | — | — | — |
Group 1 | — | — | — | — | — | — | — | — | — | — |
Group 4 | — | 1.02 | 0.40–2.60 | 0.962 | — | — | — | — | — | — |
Other | — | 1.94 | 0.85–4.46 | 0.117 | — | — | — | — | — | — |
Chronic respiratory diseases | 126 | 2.95 | 1.42–6.16 | 0.004 | — | — | — | 3.44 | 1.53–7.70 | 0.003 |
Systemic hypertension | 126 | 2.03 | 0.99–4.18 | 0.05 | — | — | — | 1.54 | 0.68–3.50 | 0.30 |
Other cardiac diseases | 126 | 2.53 | 1.21–5.28 | 0.014 | — | — | — | 2.21 | 0.98–4.98 | 0.055 |
Diabetes | 126 | 1.90 | 0.83–4.36 | 0.13 | — | — | — | — | — | — |
Chronic renal failure | 126 | 3.62 | 1.68–7.8 | 0.001 | — | — | — | 2.65 | 1.14–6.17 | 0.024 |
NYHA FC III/IV (vs. I/II) | 126 | 2.35 | 1.12–4.88 | 0.022 | 1.86 | 0.84–4.10 | 0.12 | — | — | — |
6-min-walk distance > 440 m | 100 | 0.24 | 0.08–0.70 | 0.009 | — | — | — | — | — | — |
Increased BNP or NT-proBNP | 113 | 1.89 | 0.87–4.13 | 0.11 | — | — | — | — | — | — |
Right atrial pressure (mm Hg) | 120 | 1.05 | 0.99–1.11 | 0.14 | — | — | — | — | — | — |
Anticoagulation | 126 | 0.47 | 0.23–0.97 | 0.042 | 0.47 | 0.21–1.02 | 0.056 | — | — | — |
Definition of abbreviations: BNP = brain natriuretic peptide; CI = confidence interval; NT-proBNP = N-terminal pro–brain natriuretic peptide; NYHA = New York Heart Association; PH = pulmonary hypertension.