TABLE 2.
Recovery of C. albicans from infected tissues
| Time postinfection (h) | Strain | Log10 CFU/g (mean ± SD) in:
|
|
|---|---|---|---|
| Kidneysa | Liverb | ||
| 24 | CAF2 | 6.20 ± 0.27 | 3.88 ± 0.10 |
| CSSK11-1 | 5.11 ± 0.11 | 3.43 ± 0.10 | |
| CSSK21-1 | 4.13 ± 0.12 | 3.28 ± 0.17 | |
| CSSK23-1 | 5.57 ± 0.50 | 3.53 ± 0.19 | |
| 48 | CAF2 | 6.66 ± 0.76 | 3.98 ± 0.34 |
| CSSK11-1 | 4.74 ± 0.44 | 2.42 ± 0.24 | |
| CSSK21-1 | 3.69 ± 0.24 | 2.39 ± 0.25 | |
| CSSK23-1 | 5.80 ± 0.94 | 3.47 ± 0.52 | |
| 72 | CAF2 | —c | — |
| CSSK11-1 | 4.68 ± 0.21 | 1.93 ± 0.16 | |
| CSSK21-1 | 3.52 ± 0.24 | 0.68 ± 0.85 | |
| CSSK23-1 | 5.56 ± 0.50 | 2.87 ± 0.25 | |
a
At 24 h, CAF2 > CSSK23 ≈ CSSK11 > CSSK21. At 48 h, CAF2 > CSSK23 > CSSK11 > CSSK21. At 72 h, CSSK23 and CSSK11 > CSSK21, and CSSK23 ≈ CSSK11.
b
At 24 h, CAF2 > CSSK11 > CSSK21, CSSK11 ≈ CSSK23, and CSSK23 > CSSK21. At 48 h, CAF2 > CSSK23 > CSSK11 and CSSK21, and CSSK11 ≈ CSSK21. At 72 h, CSSK23 > CSSK11 > CSSK21.
c
—, all mice succumbed to CAF2 infection by 72 h.