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. 2022 Nov 30;10(11):e005517. doi: 10.1136/jitc-2022-005517

Figure 4.

Figure 4

Phagocytosis of tumor cells with AK117 or combo with opsonizing antibodies. Phagocytosis of human Raji (A, n=5), Jurkat (B, n=4) and Ramos (C, n=6) by mouse bone marrow-derived macrophages mediated with AK117 and Hu5F9-G4 (one-way analysis of variance Newman-Kuels analysis, ***p<0.001, **p<0.01, error bars represent mean±SEM of duplicate samples). Opsonizing antibodies cetuximab and rituximab increase AK117-driven phagocytosis of HT-29 (D) and Raji cells (E), respectively.