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. 2022 Dec 1;17:37. doi: 10.1186/s13062-022-00344-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Synj2bp expression level in the liver is dynamic and shifts in response to changes in nutritional status and obesity. A Representative image of a wrappER-associated mitochondria (WAM) found in mouse liver hepatocytes. These images were obtained from serial section electron tomography and 3D reconstruction analysis [1]. B AlphaFold-predicted 3D structure of mouse Synj2bp. C Transcriptomic analysis of mouse liver showing the expression level of genes whose products participate in intermembrane tethering (data collected from [1]). D, E Anti-Synj2bp immunoblot and densitometry analyses (data analyzed by estimation statistics [24, 25]). F Synj2bp expression level in the liver of fasted (14 h) and fed (3 h postprandial) mice measured by quantitative real-time PCR analysis (p value calculated with Mann–Whitney test)