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. 2022 Dec 1;17:37. doi: 10.1186/s13062-022-00344-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Synj2bp silencing in mouse liver increases hepatic and plasma triglycerides content. A, B Quantitative EM morphometric analyses of lipid droplets (LD) in control and Synj2bp-silenced livers (p values calculated with Student’s t test). C, D Lipid content analysis in control and Synj2bp-silenced livers. E, F Immunoblot and densitometry analysis showing changes in ApoB expression in Synj2bp-silenced livers. G Changes in lipid content in the plasma of mice injected with control (AAV8-shScrambled) and Synj2bp-silencing vectors (AAV8-shSynj2bp). The right panel shows the weight of the mice that were used for this analysis. Mann–Whitney test was used to calculate p values unless otherwise indicated