Table 1.

Functions of heme proteins

Function	Relevant Heme Protein
Oxygen transport and storage	Hemoglobin, myoglobin, neuroglobin
Mitochondrial respiration	Mitochondrial cytochromes
Cellular metabolism and detoxification	Cytochrome P450 enzymes
Vasodilation	eNOS, cyclooxygenase
Endothelial and vascular integrity	eNOS
Antioxidant function	Glutathione peroxide, catalase
Cellular signaling	cGMP
Immune regulation	Indoleamine 2,3-dioxygenase
Antimicrobial defense	iNOS, NADPH oxidase, myeloperoxidase