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Renal total ATP content, NAD+ content, and NAD+/NADH ratio in whole kidney of sham and heme protein–induced AKI (HP-AKI) mice. (A) Total ATP content was significantly reduced at 8 hours after HP-AKI compared with sham mice. (B) and (C) Total NAD+ content and NAD+/NADH ratio were significantly lower at 8 hours after HP-AKI compared with sham mice. n=8 and n=10 in sham and HP-AKI groups, respectively. ***P<0.001 and **P<0.01 versus sham group.
