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Renal mitochondrial fission in sham and HP-AKI mice. Expression of (A) phospho dynamin-related protein 1 (p-DRP1) and (B) DRP1 protein was significantly increased at both 8 and 24 hours after HP-AKI compared with sham mice. Densitometry (mean±SEM), normalized for GAPDH expression, is displayed below blots. n=8 and n=10 in sham and HP-AKI groups, respectively, at 8 hours, and n=5 in each group at 24 hours. ***P<0.001 and **P<0.01 versus sham group.
