Table 1.

Inflammatory gene expression in murine HP-AKI (8 hours)

Gene	Sham	HP-AKI	P Value
IL-6	4.6±1.1	483.3±156.7	0.008
TNF-α	3.6±0.2	7.7±1	<0.001
IL-1β	1.1±0.1	2.3±0.3	0.001
MCP-1	5.2±0.8	87.5±11.2	0.008
KC	3.7±0.2	731.2±51.2	<0.001
MMP-9	1.3±0.1	3.7±0.2	0.004
PAI-1	3.9±0.5	50.8±7	0.008

Real-time RT-PCR analysis normalized for 18S rRNA expression; n=8 and n=10 in sham and HP-AKI groups, respectively. HP-AKI, heme protein–induced AKI.