Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inflammatory gene expression in murine RPTECs after 8 hours of heme treatment
| Gene | Vehicle | Hemin | P Value |
|---|---|---|---|
| IL-6 | 8.2±0.7 | 16.8±0.7 | <0.001 |
| TNF-α | 2.0±0.5 | 9.2±1.1 | 0.01 |
| IL-1β | 0.7±0.7 | 12.1±1.8 | 0.01 |
| MCP-1 | 3.1±0.1 | 21.3±0.9 | <0.001 |
| KC | 7.0±0.4 | 13.8±0.4 | <0.001 |
| MMP-9 | 2.4±0.1 | 8.2±0.4 | 0.008 |
| PAI-1 | 7.0±0.4 | 40.9±1.5 | 0.008 |
Real-time RT-PCR analysis normalized for 18S rRNA expression; n=4 in each group. RPTECs, renal proximal tubule epithelial cells.
