TABLE 2.
Interaction between Candida spp. and plateletsa
| Candida spp. | % of yeast cells bound to platelets in blood from:
|
|
|---|---|---|
| Inoculated mice | Uninfected mice | |
| C. albicans | 95.0 ± 0.2 | 1.8 ± 0.8 |
| C. albicans isolate 1 | 90.2 ± 1.1 | 1.2 ± 0.3 |
| C. albicans isolate 2 | 92.6 ± 0.8 | 1.7 ± 0.4 |
| C. glabrata | 99.8 ± 0.2 | 2.5 ± 0.9 |
| C. guilliermondii | 98.6 ± 1.3 | 0 |
| C. tropicalis | 98.7 ± 0.4 | 0 |
| C. kefyr | 96.4 ± 0.1 | 0 |
| C. parapsilosis | 99.9 ± 0.1 | 0 |
Mice were inoculated as described in Materials and Methods, and blood recovered by periorbital puncture and diluted in PBS–3.3 mM formaldehyde. Negative controls were performed as described for Table 1. Data are means ± standard deviations of three observations of six independent experiments.