Fig. 7.

Chromatin occupancy of β‐catenin in the THRA gene promoter. ChIP analysis was performed with chromatin prepared from (A) Caco2, (B) SW480, and (C) HCT116 cells and immunoprecipitated using an anti‐β‐catenin or IgG (negative control). qPCR was performed using specific primers covering each TCF7L2‐binding site within 3 kb of the THRA promoter. The results are representative of two independent experiments. Histograms represent the fold enrichment of specific β‐catenin/DNA binding normalized to the input and compared with the IgG condition (= 1).