Table 2.
Summary of study characteristics.
| ANIMAL CHARACTERISTICS | N (%) |
|---|---|
| Animal Type | |
| Rat | 11 (61.1) |
| Rabbit | 6 (33.3) |
| Canine | 1 (5.6) |
| Rat | |
| Sprague Dawley Rat | 5 (27.8) |
| Lewis Rat | 3 (16.7) |
| Athymic nude Rat | 1 (5.6) |
| Fisher Rat | 1 (5.6) |
| Syngeneic BDIX Rat | 1 (5.6) |
| Rabbit | |
| New Zealand white Rabbit | 5 (27.8) |
| Japanese white Rabbit | 1 (5.6) |
| Canine | |
| Mixed-breed dogs | 1 (5.6) |
| Age | |
| <3 Months | 1 (5.6) |
| ≥3 months and <6 months | 5 (27.8) |
| ≥8 months | 3 (16.7) |
| Not reported | 9 (50) |
| Sex | |
| Male | 7 (38.9) |
| Female | 4 (22.2) |
| Not reported |
7 (38.9) |
|
STEM CELL CHARACTERISTICS |
N (%) |
| Source | |
| Adipose | 8 (44.4) |
| Bone Marrow | 8 (44.4) |
| Umbilical Cord | 2 (11.1) |
| Origin | |
| Allogenic | 11 (61.1) |
| Autologous | 2 (11.1) |
| Xenogenic | 5 (27.8) |
| Dose | |
| ≤1 Million cells | 10 (55.6) |
| >1 Million cells | 5 (27.8) |
| Not reported |
3 (16.7) |
| EXPERIMENTAL CHARACTERISTICS |
N (%) |
| RCI Model | |
| Acute Model (intervention given ≤ 3 days after model creation) | 12 (66.7) |
| Chronic Model (intervention given 4–8 weeks after model creation) | 4 (22.2) |
| Both | 2 (11.1) |
| Delivery Method | |
| Direct Application | 4 (22.2) |
| Scaffold | 14 (77.8) |
| Measurement Modality | |
| Biomechanical - Ultimate Load Failure | 15 (83.3) |
| Biomechanical - Stiffness | 9 (50) |
| Biomechanical - Tendon Cross-sectional Area | 3 (16.7) |
| Imaging - MicroCT | 3 (16.7) |
| Histologic - Collagen Birefringence | 4 (22.2) |
| Histologic - Total Area of Metachromasia | 4 (22.2) |
| Safety | |
| Presence of infection | 2 (11.1) |
| Complication due to surgical procedure | 1 (5.6) |
| No complications noted | 6 (33.3) |
| Complications were not addressed | 9 (50) |