Table 1.
Primary and secondary patient reported outcome measures.
| DOMAIN | OUTCOME | DESCRIPTION |
|---|---|---|
| Primary patient reported outcomes | ||
| Pain intensity | 100 mm VAS: average paina | Using anchors of ‘no pain’ and ‘worst pain imaginable’, a valid, reliable and responsive measure [42]. |
| Knee-related quality of life | KOOS-QoL | 4-item scale providing scores ranging from 0 (worst) to 100 (best) points, which is reliable and responsive [43]. |
| Health-related quality of life | EQ-5D-5L | Five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Five severity levels: “no problems”, “slight problems”, “moderate problems”, “severe problems”, and “extreme problems” describing 3125 distinct health states. Most widely used generic patient reported outcome, and is valid and reliable [44]. The EQ-5D-5L index was calculated using an England-based value set [44] as it closely resembled the Australian population [45]. |
| Secondary patient outcomes | ||
| Surgery | Surgery desire | Determined through a custom developed question “Do you have so much pain and trouble from your knee that you want to have surgery?“, with answers categorised as ‘yes’ or ‘no’. |
| Functional performance | 30 s chair-stand test | Recommended by the OARSI [46], and administered by physiotherapists providing GLA:D® at baseline (prior to program commencement) and 3-month follow up. |
| Walking speed | 40 m fast-paced walk test | Recommended by the OARSI [46], and administered by physiotherapists providing GLA:D® at baseline (prior to program commencement) and 3-month follow up. |
EQ-5D-5L = European quality of life-5 dimensions-5 level quality of life scale; KOOS-QoL = Knee Injury and Osteoarthritis Outcomes Score Quality of Life subscale; VAS = visual analogue scale.
a
In previous month.