Table 5.
Pain, knee-related quality of life, and health related quality of life comparisons between baseline and 3-months, and baseline and 12-months.
| Baseline v 3-months |
Baseline v 12-months |
|||||
|---|---|---|---|---|---|---|
| Mean difference (95% CI) | Effect size (95% CI) | Responders (n = ) | Mean difference (95% CI) | Effect size (95% CI) | Responders (n = )a | |
| Average pain in previous month (mm) | 14 (11–18) | 0.73 (62–0.84) | 56% (398/716) | 15 (11–18) | 0.65 (0.54–0.77) | 55% (357/653) |
| KOOS-QoL subscale | 14 (11–17) | 0.79 (0.69–0.90) | 50% (363/731) | 17 (14–20) | 0.93 (0.81–1.04) | 53% (356/668) |
| EQ-5D-5L utility score | 0.06 (0.04–0.08) | 0.43 (0.31–0.54) | 49% (337/682) | 0.07 (0.04–0.10) | 0.46 (0.35–0.58) | 52% (326/624) |
KOOS-QoL = Knee Injury and Osteoarthritis Outcome Score quality of life; EQ-5D-5L = European Quality of Life-5 dimensions-5 levels.
a
Number of responders/number of participants with adequate data at baseline and follow up to determine responsiveness.