Table 3.

Estimated differences in mean articular cartilage thickness in different intraarticular areas post-PRP treatment (as compared with cartilage thickness pre-treatment).

Areas of measurement	No. of studies (knees)	Estimated difference in means (95%CI)	Heterogeneity
			τ2	I2	Q value	P value
MFC	5 (313) [20,22,23,27,28]	0.068 (−0.05 - 0.185), p ​= ​0.259	0.01	86.284	29.163	<0.001
LFC	4 (210) [22,23,27,28]	0.064 (−0.02 - 0.148), p ​= ​0.136	0.002	24.568	3.977	0.264
MTP	2 (87) [22,23]	−0.105 (−0.290 - 0.079), p ​= ​0.263	<0.001	<0.001	0.804	0.370
LTP	2 (87) [22,23]	−0.019 (−0.214 – 0.176), p ​= ​0.848	<0.001	<0.001	0.648	0.421
Overall (MFC, LFC, MTP, LTP)	3 (145) [22,24,26]	−0.075 (−0.300 – 0.150), p ​= ​0.513	0.017	44.705	3.617	0.164

PRP: Platelet-Rich Plasma, CI: Confidence Interval, MFC: medial femoral condyle, LFC: lateral femoral condyle.

MTP: medial tibial plateau, LTP: lateral tibial plateau, p<0.05: significant.