Fig. 3.

Cytokines measured after IL-1β stimulation. Cytokine levels were measured in supernatants from healthy controls (HC) (white, n ​= ​7) and rheumatoid arthritis (RA) (black, n ​= ​6) explants incubated with (broken line) and without interleukin (IL)-1β (unbroken line) harvested at day 0, 3, 6, 9, 14. Mean values ​± ​SEM are shown for each time point and statistical differences were calculated using Mixed effect analysis, comparing the different groups. ∗∗∗∗p ​< ​0.0001.